Practical radiobiology for proton therapy planning / (Αριθ. εγγραφής 139176)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 06039nam a2200505 i 4500 |
| 001 - CONTROL NUMBER | |
| control field | 9780750313384 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | IOP |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20201022103508.0 |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS | |
| fixed length control field | m eo d |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION | |
| fixed length control field | cr cn |||m|||a |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 180111s2017 enka ob 000 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780750313384 |
| Qualifying information | ebook |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| International Standard Book Number | 9780750313407 |
| Qualifying information | mobi |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER | |
| Canceled/invalid ISBN | 9780750313391 |
| Qualifying information | |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | CaBNVSL |
| Language of cataloging | gre |
| Description conventions | AACR2 |
| Transcribing agency | GR-PaULI |
| Modifying agency | GR-PaULI |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616.994 064 2 |
| Edition number | 23 |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Jones, Bleddyn |
| Relator term | συγγραφέας. |
| 9 (RLIN) | 173397 |
| 245 10 - TITLE STATEMENT | |
| Title | Practical radiobiology for proton therapy planning / |
| Statement of responsibility, etc. | Bleddyn Jones. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication, distribution, etc. | Bristol : |
| Name of publisher, distributor, etc. | IOP Publishing, |
| Date of publication, distribution, etc. | c2017. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | 1 ηλεκτρονική πηγή (πολίλες σελιδαριθμήσεις) : |
| Other physical details | εικ. (μερ. έγχρ.). |
| 490 1# - SERIES STATEMENT | |
| Series statement | IOP expanding physics, |
| International Standard Serial Number | 2053-2563 |
| 490 1# - SERIES STATEMENT | |
| Series statement | Series in physics and engineering in medicine and biology |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc | Περιλαμβάνει βιβλιογραφικές παραπομπές. |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 1. Particle physics for biological interactions -- 1.1. Physical beam parameters, essential dosimetry and reference (or control) radiation requirements for RBE studies -- 1.2. Physics interacting with biology |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 2. The essential radiobiology background -- 2.1. Introduction -- 2.2. Background and models -- 2.3. The [alpha]/[beta] ratio and its choice for modelling particle therapies |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 3. Some important medical and surgical considerations, including clinical trials -- 3.1. Introduction -- 3.2. Surgery -- 3.3. Cytotoxic chemotherapies -- 3.4. Age and other medical conditions -- 3.5. Interpretation of the case histories and literature -- 3.6. Clinical trials -- 3.7. Ethical issues -- 3.8. Mixed endpoints -- 3.9. The importance of follow-up -- 3.10. Publication bias -- 3.11. Some future prospects |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 4. Treatment planning and further medical perspectives -- 4.1. Introduction -- 4.2. Treatment planning processes -- 4.3. The important interaction of RBE issues with the marginal target volumes -- 4.4. Comparative planning studies -- 4.5. Trade-off situations in comparative treatment planning -- 4.5..1 Changes in the treatment plan -- 4.6. How to accommodate assumed errors in the RBE -- 4.7. The product of LET and dose |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 5. Historical development of radiotherapy including what was learned from fast neutrons -- 5.1. Introduction -- 5.2. A brief synopsis -- 5.3. Neutron therapy -- 5.4. More recent developments based on neutron studies -- 5.5. Some important conclusions |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 6. Fractionation -- 6.1. Introduction and background radiobiology -- 6.2. A brief history of fractionation -- 6.3. Modelling of fractionation -- 6.4. RBE and dose per fraction -- 6.5. Effects of regions of higher and lower dose per fraction relative to the prescribed dose for different fractionation patterns -- 6.6. Taking RBE uncertainty into account in fractionation -- 6.7. The use of the LQ model with large fraction sizes -- 6.8. Optimisation of fractionation using calculus methods -- 6.9. Other contributions to fractionation -- 6.10. Summary |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 7. The case for using a variable proton RBE -- 7.1. Introduction -- 7.2. Arguments to preserve the status quo or avoid using RBE -- 7.3. Justification of a variable RBE -- 7.4. Further considerations |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 8. A general RBE simple efficiency model for protons and light ions -- 8.1. Introduction -- 8.2. The experimental data and its limitations -- 8.3. Description of the Z-specific model -- 8.4. The graphical results -- 8.5. Conclusions and what remains to be done |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 9. Inclusion of the energy-efficiency LET and RBE model in proton therapy -- 9.1. Introduction -- 9.2. RBE uncertainties -- 9.3. Description of the quantitative model -- 9.4. Some comparisons with experimental data sets -- 9.5. Two clinical examples where PBT could be suboptimal -- 9.6. Prediction of tumour response from the RBE increment -- 9.7. Concluding discussion |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 10. Compensating for elapsed time : unintended treatment interruptions and re-treatments -- 10.1. Introduction -- 10.2. Unintended treatment interruptions -- 10.3. Summary for unintended treatment gap corrections -- 10.4. Re-treatments |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 11. Errors of Bragg peak positioning and their radiobiological correction -- 11.1. Introduction -- 11.2. Brief description of methods -- 11.3. Description of the model -- 11.4. General discussion -- 11.5. Conclusions |
| 505 8# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | 12. Additional considerations and conclusions -- 12.1. Introduction -- 12.2. Dose escalation where circumstances permit -- 12.3. Simultaneous 'sensitisation' effects by new therapies -- 12.4. Sensitivity analysis of the energy efficiency model -- 12.5. What could be achieved in a single international laboratory dedicated to high LET radiobiology -- 12.6. Conclusions. |
| 520 3# - SUMMARY, ETC. | |
| Summary, etc. | Practical Radiobiology for Proton Therapy Planning covers the principles, advantages and potential pitfalls that occur in proton therapy, especially its radiobiological modelling applications. This book is intended to educate, inform and to stimulate further research questions. Additionally, it will help proton therapy centres when designing new treatments or when unintended errors or delays occur. The clear descriptions of useful equations for high LET particle beam applications, worked examples of many important clinical situations, and discussion of how proton therapy may be optimized are all important features of the text. This important book blends the relevant physics, biology and medical aspects of this multidisciplinary subject. |
| 530 ## - ADDITIONAL PHYSICAL FORM AVAILABLE NOTE | |
| Additional physical form available note | Also available in print. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Ραδιοβιολογία |
| 9 (RLIN) | 33106 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Ραδιοθεραπεία |
| 9 (RLIN) | 120967 |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical term or geographic name as entry element | Πρωτόνια |
| General subdivision | Θεραπευτική χρήση |
| 9 (RLIN) | 173398 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | IOP expanding physics. |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE | |
| Uniform title | Series in physics and engineering in medicine and biology. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | http://iopscience.iop.org/book/978-0-7503-1338-4 |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | Dewey Decimal Classification |
| Koha item type | Electronic Resource |
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